• Researchers Estimate That About 1.8 Billion People Around the World Live With Presbyopia, A Farsighedness Condition That Can Appear As a Person Grows Older.
  • More Recent Treatment Options for Presbyopia Are Eye Drops Such As Vuity, which uses Pilocarpine Hydrochloride.
  • A New Study Found That a New Eye Drop Using Both Pilocarpine Plus Diclofenac Helped Study Participaves Impa ABILITY TO READ UP CLOSE.

Researchers Estimate That About 1.8 Billion People Around the World Live With Presbyopia-An Age-Related Eye Condition where the Lens of the Eye Stiffens, Making It Hard To See and Read Close Up.

Current Treatments for Presbyopia include reading glasses, Glasses with bifocal or multifocal Lense, Bifocal Contact Lense, or Surgery, Such as Lasik.

More Recent Treatment Options for Presbyopia Are Eye Drops Such As Vuity, Which Were Approved for Use by The Food and Drug Administration (FDA) in October 2021. VUITY CONTAINS PILOCARPINE HYDROCHLIDE, WHICH IS ALSO USED TO TREAT DRY MOUTH AND GLAUCOMA.

Now, a New Study presented at the 43rd Congress of the European Society of Cataract and Refractive Surgeons (ESCRS) Reports That A New Eye Drop Formula Using Both Pilocarpine and A Nonsteroidal Anti-Inflammatory Dry Jaeger Eye Chart – Which Tests How Well You See Close Up – By An Extra Two, Three, Or More Lines.

The Findings are yet to appeal in a Peer-Reviewed Journal.

How do the New Eye Dropps Work?

For This Study, Recruited 766 Participants Diagnos with Presbyopia. Participants were treated with the Pilocarpine-Declofenac Eye Drops at Three Different Percentages of Pilocarpine-1%, 2%, or 3%-Twice a Day.

“The Eye Drop We Studied Is Based On A Pharmacological Method That Use a Combination of Drugs That Together Act In A Benefic Medical News Today.

“In simple words, The Drops Help The Eye ‘Recover’ ITS Natural Ability to Change Focus from A to Near, Subject that is gradually lost with age,” Benozzi Said.

“This combined and personalized formulation (Different Concentrations) has to Dual Mechanism Acting Directly in the Muscle Responsible (for) Focus (Ciliary Muscle) and in the Iris, Allowing to Pinhole Effect, “She continues.

Eye Drops Help Improve Near Visual Aquity

At the Study’s Conclusion, Researchers Found That the Majority of Participants Treated With The New Eye Drops Could Read an Extra Two, Three, Or More Lines On The Jaeger Eye Chart.

“In Ophthalmology, Each Line On The Reading Chart Repreasi a Meaningful Improvement in Real Life,” Benozzi Said. “Gaining Two or Three Lines Means A Patient Who Previous Stuggled To Read A Text Message or Menu Can Now Do So With Ease.”

“The Study of the Real World That We present at the European Congress of Cataract and Refractive Surgery (ESCRS) in Copenhagen, Demonstrates That All The Patients Treated (766) Achieded J3 or Better In Near Visual Aquity, That Means That All of the Patients Gain A Functional Near Visual Acuity. “
– Giovanna Benozzi, MD

“The other result was that the patients with mild and intermediate presbyopia, Achieved A Normal Near Vision (J1.J2) eliminating the need of near eyeglasses. It’s not just just GPS, etc, ”Benozzi Note.

Eyesight Improvement from Eye Drops Last for Up To 2 Years

Additionionally, Benozzi and Her Team Found That the Vision Effect from the Eye Drops Lasted for Up to 2 Years, for a median of 434 Days.

“This is highly significant scholarship it shows the treatment is not a short-LIVed Effect,” Benozzi Explained.

“The Results of this Real-World Study and Other Studies We Made in the Past, Including A Multicenter One, Now Reinforced by Mechanistic Insight, indicate that Pilocarpine-Ddiclofenac Therapy Is Bepfective and Safe in The Medium To Long Term Term. Presbyopia, durability is essential. “

– Giovanna Benozzi, MD

“Pharmacological Treatment for Presbyopia with A Customized Combination of these Drugs Is Now A Real, Evidence-Based Option,” She Continued. “With This Formulation, Patieves Can Regain Near Vision Safely and Effectively, Without The Need for Glasses for Those Patients that are not candidates Yet (for) Presbyopia Surgery.”

“Even if we have thousands of patients (20,000) Treated with long follow-up (15 Years) with a compound formulation, Submit Further Research is Needed to Reinforce Our Data,” Benozzi Added. “We Hope to find a partner soon to internationalize this Asset.”

How New Presbyopia Eye Drops Differ from Current Treatments

MNT Spoke with Benjamin Bert, MD, A Board Certified Ophthalmologist at Memorialcare Orange Coast Medical Center in Fountain Valley, CA, About This Study.

Bert, Who was not involved in the Research, Commented that This Study Expanded on Sub of the Treatments Already Being used for Presbyopia, Such As Vuity, which Also uses Pilocarpine.

“The Difference With the drop that they used in This Study is that they added a medication diclofenac, which is a non-steroidal anti-inflamatory medication, to try to counteract sum of the side effects that have Pressure Sensation, or Even Causing to Headache, ”He explained.

Bert Said That Consideration The Fact that If We All Live Long Enough, Every Single Person Is Going To Experience The Annoyances and Challenges That Occur With Presbyopia, and So It’s a Hug Area Where Millions of People Could Be Helped with An Appropriate Treatment.

“It was would be reality nice if the direct cause of presbyopia could be treated,” I have continued. “And Again, The Thought Process Right Now is not so much that Our Muscles Get Weak As We Get Older, But rather that The Lens Inside of The Eye Gets Harder. And so it’s lesson gallerable – The Muscles aren ost uble to change iTS Shape as readily.”

“So it would be fantastic if research continue Remember Them Functioning, ”Bert Added.

CAUTION: New Eye Drops May Not Be for Everyone

MNT Also Spoke with David I. Geffen, Od, Faao, director of optometric and refractive service at the gordon schanzlin new vision in La Jolla, Ca, About This Research.

“Pilocarpine Drops for the Use in Presbyopia Have Been Approved in the Us For Several Years Now and Have Had Limited Use In This Market,” Geffen, Who Was Not Involved in the Study, Said.

However, I have advised that: “Pilocarpine Works on the Ciliary Muscle, Causing Sub Pulling On The Eye, which causes Questions for Retina Issues.

“There are severe Drops Which have come to the market and bree to be approved in the us,” I have continued. “Ecceclidine has just recently been approved, and this unique drop works only on the Iris Sphincter rather than the ciliary body. “

“This drop appears in studies to be a safer alternative than pilocarpine. Studies show This drop is More Effective With a Longer Acting Time Than The Pilocarpine Alternatives,” Geffen Addd.

“Because Everyone (Can Develop) Presbyopia, The Unamet Need for Clary and Convenience is Hage. It is important for us to develop better alternatives for Our Patients. Presbypic Drops are a good alternative to those patients Who are a unhappy with their reading Glasses and can Them.

– David I. Geffen, Od, Faao