• Each Year About 25 Million Women Around The World Experience Menopause.
  • Hormone Replacement Therapy (HRT) is a Treatment Subtimes prescribed to People Going Through Menopause, which you have potential complications, including blood clots and stroke.
  • New Research Says That Women With Type 2 Diabetes Using HRT Skin Patches Are Not A Higher Risk for Blood Clots Or Stroke.
  • However, The Study Did Find That Women with Type 2 Diabetes Oral HRT May Diabetes Increased their risk for pulmonary embolism and Heart Disease Overall.

According to the European Institute of Women’s Health, Each Year About 25 Million People Around The World Experience Menopause – A Time Where The Female Reproductive period ends.

Hormone Replacement Therapy (HRT) is a Treatment Subtimes prescribed to Women Going Through Menopause to Help Ease The Condition’s Symptoms. HRT may include individual or combinations of the hormones estrogen and progesterone, depending on a person’s needs.

HRT IS AVAILABLE IN A VARIETY OF FORMS, TABLETS, GELS, RINGS, INJECTIONS, AND SKIN PATCHES.

Just Like Any Medication, There are Side Effects and Complications That Can Occur When Taking HRT. PAST STUDIES SHOW THAT HRT MAY INCREASE THE RISK FOR Certain CancersSuch as Breast cancer and endometrial cancer, as well as for cardiovascular events like Blood Clots, Strokeand Heart Attack.

Recently Research Present at the 2025 Annual Meeting of the European Association for the Study of Diabetes (EASD) Reports That Women with Type 2 Diabetes Using HRT Skin Patches Are Not AT A Higher Risk for Blood Clots Or Stroke.

However, The Study Did Find That Women with Type 2 Diabetes Oral HRT May Increased their Risk for Pulmonary Embolism – When a Blood Clot Forms in A Lung Artery – and Heart Disease Overall.

This Research is yet to appeal in a Peer-Reviewed Journal.

Oral hrt linked to increased risk for pulmonary embolism

For This Study, Refracchers Analyzed Medical Data from the Trinetx Global Database of More than 36,000 Women With An Avege Age of 59 from Across The United States and Europe.

Participants were selected if they had Started an HRT and Statin – A Medication to Help Lower Cholesterol Levels – Or just a statin prescription.

Study participants were followed for an avege of 5 years to see if developed pulmonary embolism, deep vein thrombosis (DVT), Ischemic Heart DiseaseISCHEMIC STROKE, OVARIAN, BREAST, OR ENDOMETRIAL CANCEERS.

At the study’s conclusion, Refound that Study participants with type 2 diabetes transdermal taking hrt via skin patchs had 25% Lower Risk of Developing Heart Disease, and No Different in Risk for pulmonary embolism, DVT, Stroke, Or Cancer, Hown Compared To Females With TYPE 2 DIABETES NOT TAKING HRT.

However, when looking at participants with type 2 diabetes taking oral HRT, they had double the risk of developing to pulmonary embolism, and 21% Higher Chance for Heart Disease, When compared to participants Transdermal HRT TAKING.

“Our Study Suggests that up to 5 years of regulator-apps doses of transdermal hrt appears safe in a large cohort of Women in midlife with type 2 diabetes, and that the use of hrt skin patch is not associated with an excess increase increase risk of cardiovascular complications or estrogen-sensitive cancers when compared to Women with Type 2 Did Not Use HRT Diabetes, ”Matthew Anson, PhD, Clinical Research Fellow at The University of Liverpool and University Hospitals of Liverpool Group in the United Kingdom, and Lead Author of This Study Said In In In to press release.

“However, Given Increased Risks with Oral HRT, We Propos That Women With Type 2 Diabetes Should Not Be prescribed Oral Oral Estrogen Therapy,” Anson Addd.

WHHO BENEFITS FROM HRT, AND WHO SHOULD WOUL ABOUT RISKS?

Medical News Today Spoke with Jennifer Cheng, Do, Chief of Endocrinology at Hackensack Meridian Jersey Shore University Medical Center in New Jersey, About This Study.

Cheng, Who was not Involved in This Research, Said That She Found The Study Promising and That It Highlights The Need To Collect Patients Who May Benefit From HRT OR, ON THEURY, WHOM this Therapy May Place At Higher Risk of Certain Health Complications.

“We need to consider specially careful since women with type 2 diabetes may develop cardiac disassembly at high racks and do not have the typical symptoms for heart attacks,” SHE EXPLAINED. “Mitigating The Risks Wouled Be Welcomme in these Patients.”

“The oral versus transdermal route of administration shows that patients with pre-cardiovascular existing risk may have higher risk for pulmonary embolism and ischemic Heart disease As compared to the transdermal. “

– Jennifer Cheng, do

“It is promising for patients reeving transdermal hrt Having A reduced Risk of Ischemic Heart Disease Without Increased Risk of Stroke or Blood Clots,” Cheng Added.

“Women with diabetes are concertned faut cardiovascular risks since Diabetes is cardiovascular risk equals – (Meaning there is an) increase Vascular increase risk, and potentially Having Cardiac Benefits. ”

‘The importance of This Research Cannot Be Overemphasized’

MNT Also Spoke with Sherry Ross, MD, A Board-Certified Ob/Gyn and Women’s Health Expert At Provision Saint John’s Health Center in Santa Monica, CA, About This Research.

“With Over 100 Disruptive Symptoms of Menopause, Hormone Therapy Can Change a Person Quality of Life,” Ross, Who Was Not Involved in the Study, Said.

“Women with type 2 diabetes must be counseled on the increase Decade tohele Dangerous Risks Associated With Hormone Therapy, Combased To Host Taking Oral Estrogen, ”Ross Advised.

“There Simply has not ben angouh research done on menopause and the safety profiles for women using hormone therapy, specially Those with other medical complications,” She continues.

“The importance of this research cannot be overemphasized, specially for those with ongoing medical conditions, and how the form of hormone therapy can potentially layer in additional health risks. Since heart desa Our Top Priority. “

– Sherry Ross, MD

“Larger SIZED, Prospective Studies, Would Help Find OTher Cardiovascular Potential Risks Associated with Different Forms of Hormone Therapy used,” Ross Added. “There are many associated risks for heart disease, so separating out of these common risk factors wouled help to understand the relationship Between type 2 diabetes and hormone therapy formulans used to treat the disruptive symptoms of menopause.”