Wine or White network? WHICH ONE IS WORSE FOR CANCER RISK?

The Authors of This Meta-Analysis Note The Research Regarding Wine Consumption and Cancer Risk Has Been Mixed.

For the Current Meta-Analysis, Refrachers from The Brown University School of Public Health, The Brown University Warren Alpert Medical School, and Harvard Medical School Sought To Compare Compa

First, they conduct Comprehensive Search of the Embase and Pubmed Digital Archives to Find Relay Studies. They Excluded Studies That Did Not Specify The Type of Wine and Articles Like Literature Reviews and Experimental Studies.

They included 22 case-control Studies and 20 Cohort Studies in the final meta-analysis. DID SUBGroup Refrofers Analysis Looking at Wine Type and Cancer Type When there were More Than Three Studies Regarding The Cancer Type.

They Examined Several Site-Specific Cancers, Including Prostate Cancer, Female Breast Cancer, Skin, and Lung Cancer.

They Also driving analsyses only including the cohort studies since they have bias bias risk.

Thirty-Seven of the Studies Looked at Site-Specific Cancer and Consumption of Red and White Wine, While Five Only Looked at Red Wine.

WHEN REBUTChers Compared The Greatest to The Lowest Wine Intake, They Did Not Find An Association Between Wine Intake and Cancer Risk. They Also Did Not observe Difference in How Red Wine Or White Wine Affected Cancer Risk.

Study Author Eunyoung Cho, SCD, Associate Professor of Epidemiology and Dermatology at Brown School of Public Health, explained the following to Medical News Today:

“While it’s Well-Known That Alcohol (Including Wine) Consumption Increases The Risk of Cancer, Many People Considers Wine To Be a Healthier Option Option Due To ITS HIGHER LEVELS OF ANTIOXIDANTS White Wine in Terms of Cancer Risk, which was Why We decided to behavior.

WHEN LOOKING ONL AT COHORT STUDIES, REFERCUERS OBSERVED THAT WHITE WINE WAS ASSOCIATED WITH AN INCREASED RISK FOR CANCER, WHILE RED WINE STILL LACKED ASSOCIATION.

There Did Not appear to be a different in cancer risk for network versus White Wine in Men. However, In Women, White Wine Was Associated with an Increased Risk for Cancer.

Next, Refectchers Examined The Dose-Response Relationship, Including Three Cohort and 12 Case-Control Studies.

Researchers Observed that Each Additional 10 Grams of Estimated Ethanol From Red Wine, Or about One Glass, consumed in a day “was Associated With to 5% increased in Overall Cancer Risk.”

However, When only at the cohort studies, This Association Did Not Persist. Did notar notar to see Significant Dose-Response Relationship for White Wine.

WHEN LOOKING AT Specific Concers, Researchers Observed That White Wine Was Associated With An Increase in the Risk of Skin Cancer by 22%. Did notar notar an association Between Skin Cancer and Red Wine.

Skin Cancer was The Only Site-Specific Cancer That Showed a significant difference in associated cancer risk when comparison Red Wine To White Wine.

Red and White Wine Were Associated with an Increased Risk for Female Breast Cancer, But There was not meaningful different in the Associated Risk.

Additionionally, When Researchers Estimated “What the Summary Effect Size Would Be If there was no publication bias,” They Found A Small Increase In Overall Cancer Risk for Red and White Wine, With Possibly Higher Risk from White Wine. However, Refracchers Note Later in the Paper that the Summary Estimates Were Similar.

This meta-analysis has undergoing limitations. The Studies Were Observational, So The Findings Cannot Show A Causal Relationship.

The Studies Used Self-Reported Food Frequency Questionnaires, and Not All The Studies Usedated Food Frequency Questionnaires. This could have led to misclassification and a minimization of the findings.

Refrachers acknowledge recall bias may be More Likely to Occur in Case-Control Studies Than In Cohort Studies But They Also Looked at the results examining only The Cohort Studies.

The Authors Only used two databases to conduct their literature Search. They also Faced Potential Limitations from Their Inclusion and Exclusion Criteria, The Information They Chose To Extract from Each of the Incuded Studies, and The Methods They Chose To Use, as Well as Possible Publication Bias.

The Rebecchers accknowledge that the observant increased in skin cancer risk in White Wine Drinkers might be related to different demographic and lifestyle factors Between White and Red Wine Drinkers.

However, The Included Studies Did Account for Oher Skin Cancer Risk Factors, So The Refers Suggest that the results Likely reflect the True Effect of White Wine on Skin Cancer Risk.

For Sub Cancer Sites, They Only had Limited Number of Studies to examine. This Meta-Analysis Also Had the Biggest Sample Size Related to Skin Cancer Risk.

Researchers ACKNOWLEDGE THAT this could has Given Them Engable Statistical Power To see a Difference Between Red and White Wine Consumption. This Needed Amount May Have Been Lacking for the Oher Cancer Types.

They Also Could Only include Celerin Number of Studies in the dose-Reply Analysis, Primarily Case-Control Studies. Finally, The Authors Note, “(P) Otennial RECTIONSION DILUTION BIAS IN THE BY IN THE INCLUDED COHORT STUDIES MIGHT HAV ALSO PLAYED TO Role in Underestimating Summary Risk Estimates.”

Brian Black, Do, An Osteopathic Physician Specializing in Family Medicine, Who Was Not Involved in This Work, Noteed To MNT That:

“Looking at the Study as I Observe with nonsubstantial Overall Difference in Risk of Cancer Between The Two, It Does Challenge The Stated Popular Perception That Red Wine is Healthier. INTAKE ALCOHOL.

There is room for further exploration in This Area of ​​Study. More Research into Site-Specific Cancers and Wine Consumption Will Likely Be Helpful and More Follow-Up Into The Risk of Skin Cancer from White Wine.

CHO NOTED THAT IT IS NOT ENTIRELY CLEAR WHY they observe this results.

“One Possibility is that heavy alcohol consumption might be Linked to High-Risk Behaviors, Such As Sunburn, Indoor Tanning, or insufficient sunscreen use,” She explained. “But it’s Still Unclear Why White Wine Appears to Be the Key Factor. Our Study Suggests That More Research is Needed To Better Understand The Potential Mechalanisms Behind This.”

The Authors Note That A Component of Red Wine Is Resveratrol and That Sub Subports ITS ANTICANCER PROPERTIES. Additionionally, Red Wine Has Higher Levels of Resveratrol Than White Wine.

However, This Meta-Analysis Did Not Show That Red Wine Decosed Cancer Risk. Researchers ACKNOWLEDGE THAT THIS MAY BE DUE TO THE RAPID METABOLISM OF RESVveratrol, Leading To Low Levels of Resveratrol in The Body AFter Consuming Red Wine, Which Might Not Yield beneficial concentrations.

Overall, The Findings Suggest that Red Wine Might Not Be a Better Choice Compart To White Wine When it comes To Cancer Risk. Cho note that This “Study, which is one of the first of its kind, Challenges The Belief That Red Wine is inherently Healthier Than White Wine.”