LPG-1 Microdosing for Weight Loss: Weight Experts The Pros and Cons

According to Maria Cecilia C. Asnis, MD, FACE, Dabom, director of the center for Weight Management at Stamford Health and Assistant Clinical Professor of Medicine at Columbia University Vagelos College of Physicans and Surgeons, glp-1 microdosing is the new these tools for Weight Management.

“However, The Concept of Flexibility in Dosing and Personalization of Medication Management Is Not New In The Clinical Space,” Asnis Explained To MNT. “EVEY INDIVIDUAL PERSON HAS UNIQUE NEEDS AND GOALS – AND THE ‘DOSE’ they need to Achieve and Maintain Thos Goals is Also Unique. In that Same Vein, The Dose People Respond to and tolerate without Side Effects is also individual.”

Babak Orandi, MD, PHD, Obesity Medicine Specialist and Transplant Set the Nyu Langone Weight Management Program, and Associate Professor in the Department of Surgery and Medicine At Nyu Grossman School of Medicine, Said That For Many Doctors Who prescribes this class of medications frequently Microdosing is submissing they have already been trying.

“When I Counsel My Patients, I Tell Them That the Study Sponsors have to climb the dose monthly in clinical trials but that doesn’t mean and have to practice medicine that way,” ORANDI EXPLAINED TO MNT. “Sub patients are more responsive to loower doses than Others and Pushing Them to a faster or Higher than is needy just leads to Side Effects.”

Similarly, Kayley George, MS, RD, LD, A Registered Dieitian, and Founder of the Ditch the Diet Coaching Program,awd MNT That Microdosing Through NOOM OR ANY OTHER PLATFORM IS NOT NEEDED DIFFERENT FROM WHAT DOORS prescribes with, for Example, Ozempic – The Active Ingredient, Semaglutide, is Still The Same.

“What noom is offering, However, is Lower dose than the traditional Fda-Approved Dosing regime,” George Explained. “The Traditional Ozempic Dosing Starts at 0.25 mg (Milligrams) eleven Weekly and Is Escaled Typically Every Four Weeks. In contrast, Noom States that are two -sink at 25% or Less of the Standard 0.25 mg dose and climates at a personalized Rate.”

While Microdosing Glp-1 Medications May provides More Customized Experience, There Still Questions Regarding The Safety of this practice as ae they are currently not published studies on the process, and the Microdose May Come from Compounding Pharmacy.

Jennifer Cheng, Do, Chief of Endocrinology at Hackensack Meridian Jersey Shore University Center in New Jersey, Told MNT That, right now, LPG-1 microdosing is an experimental approach.

This Means that is not Well Studied Currently, there is no reliable Information on the Safety and Side Effects of Microdosing Glp-1, and there are no guidelines on How Microdosing Should occur.

“Safety is unknown; (It Remains) unknown if (This Approach) is good or bad,” Cheng Continued. “It Still May Trigger The Side Effects of LPG-1. Giving A Smaller Dose of Ozempic or Any Other LP obstruction. ”

George Said That Microdose Of The Drug Are Only As Safe As The Pharmacy Producing It:

“To access tohe customs doses, Noom must use Specialized Compounding Pharmacy.” Their Website Claims to Work With A ‘Leading 503b Fda-Inspected Pharmacy To Dispose Compounded Semaglutide Medication.’ They Also Highlight which the Compounding Pharmacies are Us Pharmacopeia (USP) -complynt. ”

“Although they’ve taken extensively measures to enseure safety, it’s still important to understand that composted medications are not fda -appled,” She continues. “This means the final product is not review for safety or effics the way commercial drarugs are. In addition, composedded medications are typically not Covered by Insurance.”

Mir Ali, MD, to Board-Certified General Surgeon, Bariatric arose and Medical Director of Memorialcare Surgical Weight Loss Center at Orange Coast Medical Center in Fountain Valley, Ca, Told MNT That While it is usually not Harmful to Microdose LPG-1 Medications, They May Be Less Effective.

“Though Sub Patients May Feel The Effect of these Medications at Lower Doses, Most Patients require Higher Dose to see significant results,” Ali Explanred. “It may be useful in patieves who has a achiedo your Goal Weight and are using doses to maintain their weight.”

However, “Early Data and Clinical Experience suggest that is an effortive strategy,” Orandi Commented. “People with Diabetes, particularly Severe Diabetes, tend to LESS WEIGHT WITH GLP-1S THAN PEOPLE WITHOUT DIABETES, SO MICRODOSING IS LIES LIKELY TO BE AS EFFECTIVE, THOUCH ESE SHOULD ONY BE INCREASED AS THE TOLERATE IT.”

George Said That in Her Professional Opinion, Microdosing is a Potential Option for Patients with Smaller Amounts of Weight to lose or as a Bridge to Start, Or Wean Off, regular LPG-1 medications.

“It May Also Be used to Maintenance dose After Significant Weight Loss Has Already Been Achieved,” She Added. “I Would not recommend microdosing glp-1s for individuals with meaning amount of weight to luse or known metabolic dysregulation.”

The Bottom Line is that there are Still Questions Regarding the Effectiveness and Safety of Microdosing LP-1 Medications, and This Type of Regime is not for Everyone.

“I WOUD Like People To Know That Microdosing Is Not The Normal Way First Medications are used, Though it may be ugly in Those Who has a achied the desired results or will have a lot of les weight to lise,” Ali Added.

According to George:

“Microdosing is a big trend in the weight management space but still not Fda-Approved. NOOM HIT THE NAIL ON THE HEAD-PATERS NEED ACCESS TO MORE AFFORDABLE Versions of LP Medication Innovations Improve, I Believe We’ll See More Solutions Rolled Out in The Near Future.

Experts Also Stressed The Importance of Having Medical Oversight While Using GLP-1 Medications.

“It is essential that people be medically Evaluated and Followed on method medications in the long term – not just when they are paying to subscribe to program,” Asnis Said. “In the end, if we can increase access to these tools While Maintaing Oversight, and put patient outcomes over profits, that is What Will Ultimately Move the Needle on the Proverbial Scale in the Pandemic of Excess Weight.”

And Cheng Note That: “It is Better to use Fda Approved Treatments rather than experimental and unproven treatments. ”

Moreover, “It is important to speak with your Healthcare Professional Regarding the Use of LPG-1 or Microdosing,“ I have emphasized. “There are risks, Benefits and Possible Side Effects to Medications and, if discussion, They Can Help You Navigate Through the Possible Effects.”

Finally, Orandi Offered Strategies to Help Minimize Side Effects That People Should Follow When Taking Glp-1 medications in general. “Eat Slowly,” I have advised. “Avoid Heavy, Fatty Foods, individually in the first 24–48 Hours of the Injection.