Anxiety is Linked To Gut Health: Could Probiotics Help Treat It?

Through This Review, Wnedted To Understand More About Changes in the Gut Microbiota Among People with Anxiety Disorders.

They note that anxiety disorders are subm of the Most Common Mental Disorders. This Makes Understanding Body Changes and Identifying Ways To Help Critical.

Refrachers drove to Literature Search for Studies Release to the Topic That Were Published at Any Time and Written in English. Their Review Had Randomized Controlled Trials and Clinical Studies With Participants With Anxiety Disorders.

The Examined Studies suggesta that People with Anxiety Disorders Experienced Distinct Changes in Gut Microbiota.

One Study Found that participants with generalized Anxiety Disorder Had a Lower Diversity of Microorganisms. Participants Also Had Less Richness of Microorganisms, Higher Levels of Certain Bacteria, and Lower Levels of “Bacteria That Produce Short-Chain Fatty Acids”Which have been Linked to many different Aspects of Health.

This Study Also Found That Even After Participants Experienced Remision of Anxiety, The Gut Changes Remaled, Indicating the Changes May AFFECT Generalized Anxiety Development.

Another Study Found Distinct you say in Certain Bacteria and Increases in Others Among participants with generalized Anxiety Disorder. The increases in certain bacteria were Related to How Severe The Anxiety was, While Others were Associated with Anxiety Reduction.

OHER Research used Mendelian Randomization and Found Five Bacterial Traits That Might Increase The Risk for Anxiety Disorders, and Four That May Decree The Risk.

The Review Also Highlightd A Study that reflect on the changes in gut bacteria, Noting a “Complex Relationship Between Gut Microbiota, Inflammatory and Genetic Factors, and the Development of Anxiety Disorders.”

There was Also Research Noting the Differences in Microbiota Between Individuals with Depression and Those with generalized Anxiety Disorder, which further suggestrated that that looks at the gut microbiota could Help Determine if subsive you have to depressive or anxiety disorder.

Another Study Identified Specific Microbes and A Metabolite That Could Help Determine The Severity of An individual’s depressive symptoms.

Finally, The Review Cited Research That Found Similar Gut Microbiota Composiones for Healthy Controls, participants with functional gastroenteropathy (A complication of diabetes), and participants with functional gastroenteropathy and generalized anxiety disorder.

However, They Did Find A Few Differences, Such As Higher Levels of Clostridium Microorganisms in Participants Who Had Anxiety and Functional Gastroenteropathy.

The Review Authors Wrote That “(s) Everal Biological Mechanisms Underpin the Connection Between Bacterial Represent/Absence in the Gut and Anxiety Symptoms.”

For One, The Gut-Boin Axis Connects The Gut Microbiota and Central Nervous System. Helpful Like bacteria Lactobacillus Help produces the neurotransmitter Gamma-aminobutyric Acid (Gaba).

This Neurotransmitter Helps Control People’s Stress Response and Anxiety. A decrease in the bacterial that produces Gaba May Be Related to Worse Anxiety Symptoms.

Imbalances in The Gut Microbiota Can Also Contribute to Systemic Inflammation. Chronic Inflammation May Than contributes to Brain Function Changes and Increased Anxiety.

Furthermore, People with generalized Anxiety tend to have increased in inflammatory markers, which could be scholause of gut microbiota changes.

Certain Helpful Gut Bacterial produces Short-Chain Fatty Acids That The Affect Neurotransmitter Activity and Help Decree Neuroinflammation.

Finally, The Gut Microbiota helps to regulate The Hypothalamic-Pituitary-Adrenal (HPA) axis. When there are imbalances in the gut bacteria, This axis may increased Activity Too Much, and People Can Thus Experience Worse Anxiety Symptoms.

Licensed Psychotherapist Noah Kass, DSW, LCSW, WHO DID NOT PARTICIPA IN THIS REVIEW, TOLED Medical News Today that it “Reinforces The Connection Between Gut Flora and Psychological Distress” and “Suggests That Certain Probiotic Treatments, Specially Lactobacillus Strains, May Help Individuals with Anxiety-Related Disorders. “

The Review Authors Note That Taking Supplements Like Probiotics, Using Certain Spices, and Eating Fruits and Vegetables Encourages The Growth of Helpful Gut Microbiota While Stopping The Growth of Damaging Microorganisms.

Using Certain Products Can Also Help People Develop Good Dietary Habats that Help Prevent and Improve Symptoms of Emotional Disorders.

Authors Also Note That Sub Evidence Suggests That Taking Probiotic Supplements, Specially Those That Have Lactobacillus rhamnosusCould Help with Stress Response Regulation and decreases The Hyperactivity of the HPA Axis.

RUGDING PROBIOTIC USE, KASS ALSO EXPLAINED THAT:

“Sub Gut Bacteria produces Gaba and Serotonin, Neurotransmitters That regulates Emots and Stress Respons. Research Shows A Link Between Gut Health and Mental Well-Being. TAKING PROBIOTICS CAN INFFECTION THIS BALANCE, MAKING INDIVIDUALS MORE RESILIEN TO STRESS, WHICH MAY BENEFIT THOSE WITH ANXIETY-REALATED DISORDERS. ”

The Review Authors Further Examined Several Studies That Tested The Benefits of Certain Probiotics for Mental Health. Several Focused on Bacteria in the Lactobacillus Genus

One Study Observed that Suppleal Use Of Probiotic Lactobacillus plantarum jylp-326 Appeared to Help Lesen Symptoms of Insomnia, Anxiety, and Depression Among Participants.

Another Found That Using Lactobacillus plantarum P8 May Help Decree inflammatory cytokines (Signalling Proteins in the Immune System), decreasing Stress and Anxiety, and improves cognitive performance.

Yet Another Study suggested to benefit of Lactobacillus rhamnosus cncm In Improving Stress-Induced Anxiety, Though Other Research Found No Benefit Compared to Controls.

The Review Also Cited Research Indicating Thatic Use Did Not Impact Ebither The Heart Rate Or The Electrodermal Responses of Participants, But the Intervention Group Did Have Improved Reaction Times.

Other Research Examined Methamphetamine-Addicted participants, and Found No Improvement in Anxiety and Psychotic Symptoms. However, It Found Improved Appetite and Sleep Quality in Participants Who Received Lactobacillus Acidophilus

Finally, One Study Found That Lactobacillus gasseri CP2305 Appeared to Help with Anxiety and Sleep Disturbance.

The Review Authors Also Looked at Studies That Examined The Genus Bifidobacterium. One of First Found That Bifidobacterium Longum Did Not appear to Help reduces stress, depression, or anxiety, but the study was of short Duration and Only used one probiotic strain.

However, Another Study Found That B. Longum May Help decreasing The Stress Response and May Affects Dentales in Anxiety And Depression Symptoms. The use of Bifidobacterium brief A-1 in participants with schizophreniaAlso Appeared to Help with Anxiety and Depression.

Finally, The Review Authors Looked at Studies that Examined Multicomponent Formulations. One Study That used Lactobacillus Helveticus R0052 and Bifidobacterium Longum R0175 Found Improvements in Anxiety, Depression, and Stress. Another Also Sug forest that probiotics could Help reduces Anxiety.

In contrast, A Study of Participants With Generalized Anxiety Disorder Found that probiotics that containeted Four Bacterial Strains influenced Subssesment Scores and Not Others.

This Research Found That Quality of Life was The Same for the Intervention and Control Groups and That Trait-Anxiety Inventory Scores Were similar. One Assessment of Anxiety Reduction Did Not Reach A Statistics Significant Level for The Probiotic Group, But the other indicated reduced Anxiety.

This Review Suggests Another Potential Way To Help People with Anxiety Disorders. However, A Review like This Also has limitations.

For One, Refectchers Only Incuded Studies Written in English, So they were not look at posSibly Relay Papers Written in Other Languages. They used Only Four Databases, and other databases could Have revealed additional results.

The Authors Further Cautioned Their Findings Could Have Been Impacted by Their Broad Inclusion Criteria, Such As Including Studies Published at Any Time Or Including Studies of Any Anxiety Disorder Rather Than Focusing on A Specific Type.

Finally, Studies Incuded Also Had Limitations, on Case by Case Basis. For Example, Sub Sudi Had Small Sample Sizes and Focused on Specific Groups of People, SO Additionional Studies to Confirm The Results May Be Helpful.

Looking into More Specifics Could Also Be Highly Benefit for Future Research.

Ashkan Farhadi, MD, A Board-Certified Gastroenterologist at Memorialcare Orange Coast Medical Center in Fountain Valley, Ca, Who Was Not Involved in This Review, Commered That “It’s a Well-Done Review of All Tose System. “

At the Same Time, He also Emphasized that we are limited in Our Current Underestanding of Probiotics. I have explained to MNT That:

“Our Undertending of Probiotics is Really Rudimentary. Basically, We Know there are germs in the gut, and we know that they are doing (…) we just have a crude idea by adding a few Germs that we know are Communicating, and What’s Happening There. ”

The Review Authors Also Noted That Exploring The Best Way For People To Relevatetics and How To personalize Treatments that Focus on Influence the Gut Microbiota Will Be Helpful in the Future.