- There are severe risk factors formentia, including type 2 diabetes.
- A New Study Reports That Sumaglutide-The Active Ingredient in Type 2 Diabetes and Weight Loss LPG-1 Medications Ozempic and Wegovy-May Help Lower Dementia Risk in People with Type 2 Diabetes.
- Researchers Say Semaglutide Targets Several Dementia Risk Factors, In Addiction to Being Anti-Inflammatory, Which Coud Explain This Benefit.
According to Alzheimer’s Disease International, As of 2020, There Were Over 55 Million People Living With Dementia, With That Number Expecta To Rise to 78 Million By 2030.
There Is Currently No Cure for Dementia, which is an u umbella tris for a group of brain disorders including Alzheimer’s disease, Lewy Body Dementia, and vascular dementia.
Several identified experts
Following to Healthy Diet Like the Mediterranean-Dash Intervention for Neurodegenerative Delay (Mind) Diet, Becoming More Physically Active, Staying Socially Engaged, and Lowering Your Type 2 Diabetes Risk Could All Help Prevent Dementia.
“Currently, There is no cure formentia,” Rong Xu, PhD, Professor of Biomedical Informatics and Director of the Center for Ai In Drug Discovery at Case Western Reserve University in Ohio, Told Medical News Today.
“On The OTher Hand, About 50% of Dementia Cases Are Preventable By Targeting its 14 Known Modifiable Risk Factors. However, Each Risk Factor Contribes 1% -7% to the Overall Dementia Risk. Therefore, We Need Prevention Strategies That Can Simultaneous Simultaneous Target Multiple Dementia Risk Risk Factors, ”Xu Explained.
Xu is the lead author of a new study WHICH FOUNT THAT
The Findings Were Published in the Journal of Alzheimer’s Disease.
WHY Semaglutide Formentia Prevention?
For This Study, Refrachers Analyzed Electronic Health Record Data from More than 1.7 million adults in the United States with Type 2 diabetes.
Study Participants were followed for three years to see they developed ne
In Addition to Semaglutide, Scientists Also Looked at Other Type 2 Diabetes Medications, Including Insulin, Metformin, and Older Generation GLP-1S.
“Semaglutide Is Highly Effective in Simultaneously Targeting Several Dementia Risk Factors, including obesity, diabetes, and
“In Adionion, Semaglutide has anti-inflammatory effects, and inflammation plays a significant role in the unfortunate and progression of all-cause dementias,” She continues. “You are suggest that semaglutide could be an effective pharmacological prevention Strategy for dementia in high-risk populations such as patients with type 2 diabetes.”
Semaglutide Use Helps Lower Vascular Dementia Risk
At the Study’s Conclusion, Researchers Found That Participants Taking Semaglutide had a significantly Lower Risk of Developing Vascular Dementia than Thue Taking Taking Any Other Type 2 Diabetes Medication, Including Other Glp-1s.
“Our Findings Show Evidence that Semaglutide Treatment in Patients With Diabetes Appears to Protect From Vascular Dementia and Other Dementia, but not Frontotemporal Or Lewy Body Dementia,” Xu Explained. “In Adionion, This is an Associational Study and no Causation Can Be Drawn.”
“For People Concerned About Dementia, This Information Can Guide Decions on Choking Anti-Diabetic Medications for Diabetes Management While Mitigating Dementia Development,” She Added.
For the Next Steps in This Research, Xu Said The Team Plans to Examine If
“Preclinical and Clinical Studies are Necessary to Understand The Mechanisms and establish Causal Effects Through Randomized Trials,” She continues.
“Economic and policy analyzes are Needed to examine the cost-effectiveness of integrating semaglutide and other pharmacotherapy-brased prevention Strategies with existing behavior-based approaches, such as exercise and diet in a achieving substantial benefits for preservation cognitive function and preventing and preventing Dementia, ”Xu Note.
How Might Semaglutide Help Lower Dementia Risk?
MNT Spoke with Mir Ali, MD, A Board-Certified General Surgeon, Bariatric Surgeon and Medical Director of Memorialcare Surgical Weight Loss Center at Orange Coast Medical Center in Fountain Valley, Ca, To Find Out More About How Semaglutide Might Be Uble to Help Lower A Person’s person.
“This Class of Medications are in WidesPread Use and Currently The Most Effective Weight Loss Medications Available,” Ali, Who Was Not Involved in the Current Study, Explained. “Finding All The Effects of Tohese Medications May Expand Possible Indications for First Drugs and Possibly Increases Insurance Coverage.”
Hypothesizing on potential mechanisms of prevention, Ali Told Us:
“To My Knowledge the Exact Cause of Alzheimer’s Dementia is unknown; Obesity in General Causes to Chronic Inflamatory Process Through the body and This Can contributes to many medical issues. Perhaps The Decree In Chronic Inflammation May Lead to reduction in dementia risk.”
MNT Also Spoke to Manisha Parulekar, MD, FACP, AGSF, CMD, Director of the Division of Geriatrics at Hackensack University Medical Center, and co-director of the center for memory loss and brain health at hakensack University Medical Center in New Jersey, About The Current Research.
Parulekar, Who was similarly not Involved in This Study, Commented that People With 2 Diabetes Have a signantly Increased Risk of Developing Alzheimer’s Disease and Other Forms of Dementia, and This Research Suggests A Shared Underlying Mechanism or Pathway.
“Adionionionally, LPG-1 recipient Agonists (Semaglutide Like) has shown neuroprotective effects,” Parulekar Continued. “Preclinical Studies (In Animals) will have demonstrated that GLP-1 Agonists Can Protect Neurons, reduces inflammation in the brain, and improves cognitive function.”
“SEMAGLUTID ALSO IMPROVES INSULIN SENSITIVITY AND GLUCOS CONTROL, AND ALSO PROMOTES WEIGHT LOSS Can Also Improve Cardiovascular Health, which is Linked to Brain Health. ”
– Manisha Parulekar, MD, FACP, AGSF, CMD
“Lastly, Other Diabetes Medications Have Shown Potential Cognitive Benefits,” She Added. “Sub Sudies have suggested that Other Diabetes Medications, Such As Metformin, May Also Have Protective Effects Against
