• Refrofers Based in the United Kingdom Recently Examined How LP-1 Agonist Drugs Impact Asthma in People With Obesity.
  • PEOPLE TAKING GLP-1 MEDICATIONS HAD BETTER-CONTROLLED ASTHMA OVERALL, THOUCH there was no difficult in lung function compared to those not taking glp-1S.
  • The Study Suggests that GLP-1 Drugs May have anti-inflammatory effects that benefit the lungs.

Healthcare Providers OFTEN prescribes LPG-1 Drugs Such As Semaglutide (Ozempic and Wegovy) or Liraglutide (Victoza and Saxnda) for Type 2 Control and Weight Loss Diabetes. As these medications increased in Popularity, Refectchers Are Looking into other ways tohe drarugs can be useful.

Recent Research Shows That LP-1 Medications May reduces Obesity-Related Cancer Risk and May Lower Dementia Risk.

Refrachers from The University of Aberdeen and the Observational And Pragmatic Research Institute in the United Kingdom Recently Examined How Tosee Medications Impact Asthma Control in People With Obesity.

They Found That People Taking Glp-1 Medications Had Better-Controlled Asthma Overall.

The Findings are published in the Journal Advances in Therapy.

Examination Howlp-1 Drugs Impact Asthma

LPG-1 Agonists are a Type of Medication that Mimic The Hormone Glucon-Like Peptide-1 to Help Regulate Blood Sugar, increase insulin secretion, reduces Gastric Emptying, and increases Appetite Satiety.

These Medications Treat Type 2 Diabetes and Assist in Weight Loss in People Who Are Eithher Overweight or Have Obesity. LPG-1S have shown anti-inflammatory effects, and since An inflamatory responsibility triggers asthmaRefrachers in the Current Study Wanted to See What Effects Best Medications have on People With Obesity and Asthma.

The Study Examined Around 60,000 People, Including More than 10,000 People with Both Obesity and Asthma Taking Glp-1 Drugs and Arund 50,000 Matched Controls. The Refrachers used data from the optimum patient CARE Research Database.

In Order to Qualify for Inclusion in the Study, The Participants Needed to have had an Asthma Consultation in the 12 months Before Starting the LPG-1 medication. They Also had to be at least 18 years old and have a Body Mass Index (BMI) of More than 30, which indicates obesity.

EACH Participant in the LPG-1 Group was matched 5: 1 with participants who had similar Characteristics But Had Not Taken GLP-1 medications.

People on LPG-1 Drugs Had Marked Asthma Improvement

The Refers used an avege of 3 years of follow-up data to determine how well People with Asthma who were on glp-1 medications Did compared to People in the matched group.

They used the participants’ Baseline Risk Domain Asthma Control (RDAC) and Overall Asthma Control (OAC) Scores and Compared toSe to Scores Taken During During Follow-Up.

While the LPG-1 Group had a higher average bmi and worse asthma control Before starting the glp-1 drarugs, they had “significant” improvments in their asthma scores After being on the glp-1 medication for a year.

The LPG-1 Group Did Not Differ Much from The Matched Group at the End of the Study In Terms of Lung Function. The Authors Point To Missing Data Due to the Covid-19 Pandemic On This Measurement.

“Obese Asthmatics are unique in that they are Often Steroid-Resistant, and It is positive that mechanistic Differences in obese Asthmatics and Weight Loss With GLP1 May Have Pleomorphic Effects on Inflammation Beyond Just Weight Loss,” The Study Authors Note.

Overall, The Study Findings Demonstrarate That Glp-1 Medications have the potential to positively impact asthma in People with Obesity. Further Research is Needed, Though, Specially to Determine WHETHERS MEDICATIONS CAN ONE DAY BE USED TO TREAT APIRATORY ISSUES.

Disagree on Whether LP-1 experts contribute to asthma control

Jimmy Johannes, MD, Pulmonologist and Critical Care Medicine Specialist at Memorialcare Long Beach Medical Center, Spoke with Medical News Today About the Study.

“This Study Further Supports the Link Between Weight Loss, In This Case With Glp-1 Drugs, and Improved Asthma Control,” Said Johannes. “It Also Raises The Possibility That Glp-1 Drugs May Be Helpful for The Treatment of Asthma.”

Johannes Discuced The Mechanism by Which The LPG-1 Drugs Improved Asthma and Noteed That There Are Glp-1 recets in the lungs.

“LPG-1 AgonistS May Be Uble to Directly RECEPOR Reduces the inflammation and airway hyperscripnivess that contributes to Asthma,” Johannes Explanined.

Thomas Kilkenny, Do, Director of the Institute of Sleep Medicine, Pulmonary & Critical Care At Northwell’s Staten Island University Hospital, Also Spoke With MNT About the Study.

Kilkenny Did Not Think The Study Adequately Demonstated That Glp-1 Medications Were Responsible For The Improved Asthma Control and Sugged Cat The Improvements Could Be Related To Weight Loss.

Is it glp-1s or weight loss?

“It has been shown multiple Times in the Past, and Various Studies Show that Weight Loss Alone Improper Ashma Control. This Study Did Not Comment on Whether The GLP-1 Medication Had A Direct Effect on The Physiology of Asthma Control.”
– Thomas Kilkenny, do

Kilkenny Explained That Weight Loss Alone Improvs ASTHMA Control For Several Reasons, Including “A decrease in the low-degrade inflammation that is associated with obesity.”