• Intrinsic Capacity is The Sum of A Mental and Physical Capacities, and is a Measure of Aging.
  • MAINTAING Physical and Mental Function is a cornerstone of healthy aging.
  • Formerly, Assessing Intrinsic Capacity Has Been at Costly and Time-Consuming Process.
  • NOW, Researchers have revealed Method for Assessing Intrinsic Capacity and Age-Related decline from a single drop of Blood or Saliva.
  • They suggest that their test could be used to track aging and guide targeted interventions to maintain mention and Physical Function As People Age.

Intrinsic capacity (IC) is defined by the World Health Organization (WHO) As “All The Physical and Mental Training That a person can draw on and includes their ability to walk, Think, See, Hear and Remember.”

A person’s intrinsic training is influenced by a number of factor, including the witness of designs, injuries and age-related changes.

Maininting Your Intrinsic Capacity is Key to Healthy Aging. However, Measuring Intrinsic Capacity Has, Until Now, Required Sophisticated Equipment and Trained Personnel.

A New Study Has Found That Measuring DNA METHYLATION In Blood Samples to Assessic Capacity Effectively Predicts All-Cause Mortality.

The Study, which is published in Nature Agingsuggests that the Ic CLOCK COULD BE A USEFUL TOOL FOR TRACKING AGING AND GUIDING TARGED INTERVENTIONS TO MAINTAIN FUNCTION IN OLDER AGE.

Thomas M. Holland, MD, MS, A Physician-Scientist and Assistant Professor at The Rush Institute for Healthy Aging, Rush University, College of Health Sciences, Who Was Not Involved in This Study, Commented For For For Medical News Today That:

“A Blood- or Saliva-Based Test for Intrinsic Capacity, Known As Dnam ic, is a Vary promising tool in aging science. (…) This tests uses dna Methylation Patterns, Chemical Tags that regulates gene gene gene activity, to estimate your ic biological Functioning to your chronological age. “

“One of the Most Critical Aspects is that This Help Prevent Future Health Problems, ”Holland Explained.

Elena Rolt, MSC, Dipion, IFMCP, A Registered Nutritional Therapist and Functional Medicineoner and Cofounder of Health Miro, Who Was Not Involved in This Research, Also Welcomed The Findings.

“The DNA Methylation-Based Intrinsic Capacity (Dnam ic) Test Shows Significant Potential As A Practical Measure of Biological AGING,“ Rolt Told MNT. “Unlike Traditional Epigenetic Clock Based Tests, It Also Captures Functional Aging More Directly.”

“As it reflects immune aging, Physical Capacity and Lifestyle-Related Risk Factors, This Test May Be particularly Relay for Personalized aging interventions and preventive strategies,” She Added.

“However,” Rolt Cautioned, “ITS USE SHOULD BE COMPLEMENTARY TO OTHER MARKERS – EG PHENOAGE, GRIMAGE, FUNCTIONAL TESTS – AND ITS UTS USE IN CLINICAL PRACTICE PRACTICE DEPEND ON FURTER VALIDATION.”

Blood and Saliva Samples Shed Light on Cellular Aging

Using Data from 1.014 People from the inspiration-t Cohort, Aged Between 20 and 102 Years, The Researchers Developed An ic Score Using Five Aspects of Age-Related Decline:

  1. cognition
  2. Locomotion
  3. Sensory (Vision and Hearing)
  4. Psychological
  5. Vitality.

From Blood and Saliva Tests, The Researchers Collected Data On DNA METHYLATION – A Process that Activates or Deactivates Genes. DNA METHYLATION CHANGES OVER TIM Abnormal Methylation Patterns Have Been Linked to Several Diseases.

They used this, and the age-relaced decline data, to construct an Epigenetic Predictor of IC (AN “ic CLOCK,” OR DNAM IC), THEN EVALUATED ASSOCIATIONS BETWEEN THE IC CLOCK AND MORTORITY.

The Researchers Found That Dnam IC was Strongly Associated with Overall Health. People with the Highest Dnam ic Had Better Lung Function, Faster Walking Speed, Greater Bone Mineral Density and Were More Likely to View Themselves as Healthy.

And People with a High Dnam ic LIVED, On Avenge, 5.5 Years Longer Than Thue with A Low Dnam ic.

HOLLAND TOLED US THIS WAS A VERY SIGNANT FINDING: “Scientifically, This Reflects Strong Associations Between High Ic and Better Immune Function, Lower Chronic Inflammation, and reduced Risk for Deseas Like Hypertension, Heart Failure, Stroke, Stroke, And other Age-Related Conditions. “

“Simply,” I have added, “If your body is functioning Well Internally you are like Like Live Longer and Stay Healthier. This Test Doesn’t Just Give A Snapshot of Your Current State; It May Also Offer a Glimpse into your future future Health.”

Can You Improve your Intrinsic Capacity?

In Everyone, Intrinsic Capacity Declines With Age, But there are Measures That Can Help To Slow That Decline.

This Study Found That People with A High Dietary Intake of Oily Fish, and Sugar Intake That Was Within recommended Guidelines (no more than 5% of Total Energy INTAKE), Were More Likely to have a high dnam ic.

Tunç Tiryaki, Board-Certified Plastic Armengon and Founder of the London Regenerative Institute, Who Was Not Involved in the Recent Study, Explained The Association:

“Oily Fish Are Rich in Long-Chain Omega-3 Fatty Acids (EPA and DHA), which has anti-inflammatory, neuroprotective and mithochondrial-SPORTIVE PROPERTIES. These mechanisms are closely Alledned with Domains of ic Such as vitality and cognitive function. Omega-3s Also Modulate Gene Expression Related to Immune Respons and Cellular Senescence, Pathways Shown to be enriched in the dnam ic signature. ”

“Conversley, excessive sugar intake is Known to accelerate glycation, oxidative stress, insulin resistance and chronic inflammation, all of which unpair ic,” tyrayaki toled MNT.

“Staying Within recommended sugar limits Likely supports metabolic flexibility and reduces inflammatory burden, conserving cognitive and physical function .Se dietary factors Likely influence dnam ic by modulating epigenetic regulation and immune aging, Thus Helping Mag Capacity, “He Detailed.

How to Extend Your Healthy Life Years: Expert Tips

Holland, Teringoki, and Rolt recommended Number of Measures to Help Reure Healthy Aging. These include:

  • Following to Healthy Diet, Such as The Mind or Mediterranean Diet, That Is Rich In Fresh Fruit and Vegetables, Wholegrains, and Healthy Fats, Such As Those Found In Nuts, Olive Oil And Oily Fish
  • Regular Physical Activity, Including Aerobic Activity, Strength Training and Balance Exercises; Shrayaki Emphasized that Physical Activity “Supports Locomotion and Vitality and Influences Mithochondrial Function and Immune Health, Both of Which are Linked To IC”
  • Cognitive and Social Engagement – Keeping Your Brain Stimulated and Social Maininting Networks Are Both Associated with Healthier Aging.
  • Reningy You Manage Stress and Any Chronic Diseases.

HOLLAND TOLED US That The Dnam Clock was a Major Advance in Functional AGING SCIENCE: “It The Groundwork For Using Personalised Epigenetic Markers to Guide Interventions in Preventive Geriatrics, Longevity Medicine and Precision Public Health. ”

“Dnam ic reflects not Only How Long You Might Live, But How Well You Might Function, and That Shift in Focus is Central To Meaningful Longevity.”

– Thomas M. Holland, MD, MS